I have a ChIP-seq dataset of transcription factor A. There are genomic regions that we are interested in. Region 1 is 6 million base pairs and region 2 is 14 million bases. We found that there are 1500 ChIP-seq peaks per megabase in region 2 and 200 ChIP-seq peaks per megabase in region 1.
How would I test whether this difference in enrichment is significant? Any help is greatly appreciated.