plink --interaction --parameters!!
0
0
Entering edit mode
3.2 years ago

Hello

I am studying gwas research and genetic-environment interaction.

plink --bfile myfile--pheno diz.txt --pheno-name diz--logistic --ci 0.95 --covar diz.txt --covar-name AGE,SEX,BMI --allow-no-sex --interaction --parameters 1,2,3,4,5,6,7,8 --snps-only just-acgt --out result.

In this case, none of the analyzed values ​​of the variables appear, and the covariate also appears as NA.

  • I dont know how to set the order of parameters
  • How is 1,2,3,4,5,6,7,8 determined?
  • How to write the header of environment variable when 1,2.3.4.5.6.7.8 of parameters is determined
  • How to make the structure of the txt file?
  • I don't know how to write environment variable headers, etc..
SNP plink • 1.4k views
ADD COMMENT
0
Entering edit mode

Hi, you posted this question already. Can you confirm that you have read the PLINK documentation? The functioning of --parameters is explained —with examples— here: https://www.cog-genomics.org/plink/1.9/assoc

ADD REPLY
0
Entering edit mode

Hi, I read the plink description below, but I dont understand. I want to analyze the interaction of genome x environmental variable and genome x covariate.

Which option formula to use

ADD REPLY
0
Entering edit mode

Great. By the way, these are the same thing: genome x environmental variable == genome x covariate

You are already specifying covariates via: --covar-name AGE,SEX,BMI

Your covariates file (diz.txt) is the same as your phenotype file (diz.txt)?

The order of the sample entries in diz.txt must be the exact same as the order of sample entries in myfile

ADD REPLY

Login before adding your answer.

Traffic: 1948 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6