Best way to find orthologous gene between two distant species

Question

[dongzhang0725]

Hello I am studying the interaction between parasite (flatworm) and fish. I sequenced a parasite genome, and have annotated the protein genes, I want to find their orthologues in fish, as far as I know, the following two methods may achieve this:

1. use OMA or Orthofinder;
2. use reciprocal BLAST

But I am not sure which method is the most accurate and if there are other suitable methods.

[Sishuo Wang]

Hi,

You may want to try this one https://academic.oup.com/gbe/article/12/12/2258/5918455.

[dongzhang0725]

Many thanks, I will have a look at this.