Estimate ploidy and purity in cancer targeted sequencing

Question

[rosefroehlich]

Hi everyone,

I am looking for a tool to estimate ploidy and purity in cancer in order to calculated the exact cancer cell fraction with a given mutation. I am used targeted sequencing for mutation detection. However I only find tools for wgs or exome sequencing and not -as I need it- for targeted sequencing.

I would be grateful for ideas!

Thanks a lot! Rose