Population Genetics WGS: how do I know if I have too few individuals?
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3 months ago

I am having a difficult time finding information about a minimum threshold for number of individuals to use in wgs pop gen analyses. Are there software or formulas/theory available to determine what number total number of haplotypes/individuals you need to get theta estimates, make a linkage map, run mk tests etc based on inputs such as genome size, read depth per individual, sequencing platform? Obviously there can financial constraints and considerations to make for non-model organisms when choosing how many individuals to sequence. Any advice would be appreciated.

wgs sequencing next-gen • 142 views
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