Question: Given Unlimited Resources, What Would Be Your Dream Experiment?
6
gravatar for Damian Kao
7.0 years ago by
Damian Kao15k
USA
Damian Kao15k wrote:

Here is kind of a fun question: (mods feel free to move this post if you feel it doesn't belong here)

Let's say there are technologies available to fully sequence genomes/transcriptomes/whatever with extremely high accuracy and completeness. You are given enough resources to do whatever you want (within reason), what would be your dream experiment/project?

• 2.5k views
ADD COMMENTlink modified 7.0 years ago by Manu Prestat3.9k • written 7.0 years ago by Damian Kao15k
8
gravatar for Will
7.0 years ago by
Will4.5k
United States
Will4.5k wrote:

Measure the expression level of every gene in every tissue in every individual for their entire lifetime.

ADD COMMENTlink written 7.0 years ago by Will4.5k

I would add polymorphisms and regulatory regions to that :)

ADD REPLYlink written 7.0 years ago by Sudeep1.6k
2

If you did RNA-seq you'd get that info too :)

ADD REPLYlink written 7.0 years ago by Will4.5k

I would also add some characteristics such as age, weight, size, hair color, eye color........ to infinity and beyond.

ADD REPLYlink written 7.0 years ago by Maxime Lamontagne2.1k
4
gravatar for Manu Prestat
7.0 years ago by
Manu Prestat3.9k
Marseille, France
Manu Prestat3.9k wrote:

The same as now but with the 3 "R" rule: Replicates, Replicates and Replicates!!

ADD COMMENTlink written 7.0 years ago by Manu Prestat3.9k
3

++++1

This is so true, and yet so quickly forgotten when planning an experience... ;-)

ADD REPLYlink written 7.0 years ago by Leonor Palmeira3.7k
3
gravatar for Mary
7.0 years ago by
Mary11k
Boston MA area
Mary11k wrote:

I would take a small island of some sort--probably with a lighthouse--and sample everything I could. Tide pools, soil, every plant, every animal, every lichen, every mold, anything I could grab a sample. And catalog the whole thing.

Of course, I'd have to live on the island.

ADD COMMENTlink written 7.0 years ago by Mary11k
3

I would go to Australia for that :-) Very nice place to study evolution!

ADD REPLYlink written 7.0 years ago by Leonor Palmeira3.7k

That's a cool idea too :)

ADD REPLYlink written 7.0 years ago by Will4.5k
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