Any tool to mask specific probe sequence in an alignment bam file
0
0
Entering edit mode
7 weeks ago
Ken ▴ 10

We have a dataset which contains probe sequences in front of DNA fragments. We need to keep the probe sequence for the alignment to ensure alignment accuracy. After alignment, we need to mask the probe sequence before variant calling. Is there an existing tool to mask the probe sequence in the alignment bam file before variant calling? If not, what strategy would you suggest to do this?

bam masking probe • 140 views
ADD COMMENT

Login before adding your answer.

Traffic: 2437 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6