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• Recombination And Positive Selection
  Hi All, As recombination events can be misinterpreted as selective pressure events. Is it right ...
• Best way to phase regions with known recombinations?
  Hi, I have SNP data for nuclear families with at least three children where one child has a dise...
• best practices in trio snp and cnv analysis
  Hi all, I have Illumina omni5 array data for a family affected by a different grade neurological...
• What are the best tools/practices for CNV (structural variation) detection/analysis for Illumina family data?
  Hi, I am looking for the current state-of-the-art tools/practices for CNV (structural variatio...
• Simulating Trio Data
  Which tool could be used to generate/simulate parents-offspring whole genome sequences (human) in...
• What Is The Best Tool To Detect Ibd In A Trio (Mom, Dad, Child)
  I have snp data obtained from nuclear families and I want to detect "extended regions of autozygo...
• Linkage disequilibrium analysis of EUR populations from 1000 Genomes phase3 data: Considerations of singletons vs family trios
  I am interested in calculating LD and R^2 values for a region of interest using Haploview. I am i...
• Is it possible to do linkage analysis using relatives from a family, without any trios or siblings ?
  I am trying to do some linkage analysis using exome sequencing data. I have exome data of three p...
• phase genotype data (infer haplotypes) for multiple families
  Hi eveyone, could you please suggest me some software to phase genotype data for multiple famili...
• SNP Calling Parameter Settings
  Hi everyone, I am using family trios data to run GATK's SNP calling pipeline. The HaplotypeCalle...
• Forward simulation with SNP data
  Hi, I want to simulate migration events, mutations and recombinations on real snp data, by forwa...
• How to get IDs of family trios in 1000 genomes project?
  I know that several populations from the 1000 genomes project have trio data on them, but I just ...
• Detecting Crossing Over Breakpoints In Chromosomes
  I have SNP data from two parents and two offspring in a plant. I want to detect breakpoints/cross...
• Can we identify the SNP associated with "What color is this dress" by today?
  You have probably heard about the story of this dress, that some people see blue, and other white...
• Estimating SNP heritability for related individuals from a SNP array
  Hi, I am analysing some SNP data and need to calculate heritability (h2) for the SNPs I identify....
• 1000 Genomes Yri Trio, Ncbi36/37 And Rs334
  I was asked to download the data of a trio of YRI from the 1000genomes Project. So I looked at al...
• Genes involved in recombination
  Sorry if this is a bit of a silly question, but I'm looking for a few opinions on my methods.... ...
• Genomic Prediction data sets for half-sib and full-sib family
  I am developing a methodology on genomic prediction using half sib and fullsib family and applied...
• How To Calculate Recombination Rate From R^2 Data?
  If all I have is NGS and a few isolates, is there any way to calculate recombination rate? Based ...
• DNASP analysis of recombination, is my analysis meaningful?
  Hello, I am looking at 5 isolates of a diploid fungus, and have been able to align the genomes o...
• Pedigree selection from a huge family based data.
  Dear all, I need to select pedigrees from a huge family based data such that two related subject...