Question: Biomarkers Vs Markers
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gravatar for ruru
8.1 years ago by
ruru20
ruru20 wrote:

Hai. anyone can comment the differences or similarity between markers and biomarkers?

snp • 3.6k views
ADD COMMENTlink written 8.1 years ago by ruru20
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gravatar for Alex Paciorkowski
8.1 years ago by
Rochester, NY USA
Alex Paciorkowski3.4k wrote:

They're not the same thing.

A "marker" is an older term that (usually) non-geneticists use to refer to what the rest of us usually refer to as SNPs or indels or some other feature of the genome (even a mutation) that is (usually) associated with risk for a condition/disease or causative of the disease. This term in the genetics context is probably confusing, since it doesn't separate coincidental associations from biologically important genomic features. It's an overly descriptive term.

A "biomarker" is usually meant as some physiologic value that helps either with early diagnosis or prognosis -- for example, we speak of "biomarkers" for Alzheimer's disease or cancer as something we can measure in the patient that may provide a clue as to what is happening early in the disease process. Biomarkers are therefore regarded as important early discriminators of disease severity, and could be used to guide therapy.

"Marker" chromosomes, of course, are something completely different...

The question could have provided a little more detail and context -- but nevertheless, welcome to the site.

ADD COMMENTlink written 8.1 years ago by Alex Paciorkowski3.4k

hi Alex. i agree with your answer especially when marker is clearly associated with chromosome. it's always happened to me when people asking me what's the different between biomarkers and markers. this is due to a group that doing a metabolomic research and they would like to develop a biomarker based on their pathway. i can explain the different but i need more info from others to help me more clear in both terms. thanks again.

ADD REPLYlink written 8.1 years ago by ruru20
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gravatar for Josh Herr
8.1 years ago by
Josh Herr5.7k
University of Nebraska
Josh Herr5.7k wrote:

Sounds like the same thing to me. What would be the context of your question?

You've had a couple of awkwardly worded and unclear questions just in the last couple of hours, perhaps it would be a good idea to read this informative article, written by some of the contributors here, about how to maximize the resources of the BioStar community.

ADD COMMENTlink modified 8.1 years ago • written 8.1 years ago by Josh Herr5.7k
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