I have an alignment in standard FASTA format and would like to convert it to the PHYLIP format. This, by itself, is not complicated. The problem is that the alignment I'm trying to work with is the full current release of the Silva database. All implementations of this conversion I've tried until now attempt to load all sequences in memory which always falls into swap space and finally gets killed on my 8GB workstation.
Do you know of a quick solution ?
Thanks in advance !
If you have to know, I'm trying to convert it to PHYLIP for input into RAxML.