I would like to run the basic command for the meta-analysis as follow:
plink --meta-analysis study1.assoc study2.assoc
PLINK will search the header row for the columns:
- SNP SNP idenitifier
- OR Odds ratio (or BETA, etc)
- SE Standard error of OR (or user-defined weight field)
- P (Optional) p-value from test
My problem is that file 2 (
study2.assoc) does not contain SE (standard error) numbers. File
study2.assoc contains three columns named SNP, OR and P. Is there a way to calculate the SE based on these three columns? The three columns is the only information that I have.
I hope that someone can help me with this problem!