I have been working with a couple of human alternative isoforms listed in uniprot database. Now I would like to expand the study and check hundreds of transcripts.
Complete proteome file available at Uniprot provides protein sequences for each isoform but does not include any information how each isoform differs from the canonical isoform.
Does Uniprot provide this information for all available isoforms in some workable format (e.g., some flat file)?
I am interested in identifying distinct types of alternative splicing (e.g., skipped/missing exon, mutually exclusive exons etc.) for such transcripts.
I would like to stick to Uniprot for this analysis.