Question: Absolute Copy Number And Relative Copy Number
0
gravatar for xiguoyuan
6.5 years ago by
xiguoyuan0
xiguoyuan0 wrote:

Hi, I am working on copy number alteration analysis. What I got from TCGA project is .CEL datasets, which is transferred to log2 ratios after normalization and segmentation processes. What is the relative copy number and absolute copy number?

copynumber • 4.8k views
ADD COMMENTlink modified 4.8 years ago by Biostar ♦♦ 20 • written 6.5 years ago by xiguoyuan0
0
gravatar for Devon Ryan
6.5 years ago by
Devon Ryan92k
Freiburg, Germany
Devon Ryan92k wrote:

What is the relative copy number and absolute copy number?

It's the same as relative vs. absolute anything. See, for example, this link. In short, absolute always refers to the actual number of something. So, 4 copies of a genes in patients vs. 2 copies in normal controls would be a typical example. The relative copy number, then, would be that there are twice as many copies in patients vs controls.

ADD COMMENTlink written 6.5 years ago by Devon Ryan92k
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