Question: Haplotype Blocks Identification Based On Several Snps
gravatar for vlata119
4.9 years ago by
vlata1190 wrote:

Dear all!

I'm working on the following task. Our lab guys have genotyped a couple of SNPs related to a particular disease. I need to reconstruct haplotype blocks consisting of those SNPs.

Plink software,, seems to be an appropriate solution, but I get stucked with it. Still haven't tried other software solutions like Haploview, Beagle, etc...

Any suggestions are highly appreciated!

Mvh, vlata119

haplotype snp • 1.4k views
ADD COMMENTlink modified 4.9 years ago by anin.gregory70 • written 4.9 years ago by vlata1190

Do you have pedigree data or unrelated individuals? Where do you get stuck in plink?

ADD REPLYlink written 4.9 years ago by Zev.Kronenberg11k
gravatar for anin.gregory
4.9 years ago by
United States
anin.gregory70 wrote:

You should read: Jeffreys, A.J., L. Kauppi, and R. Neumann, 2001. Intensely punctated meiotic recombination in the class II region of the major histocompatibility complex. Nature Genetics 29: 217-222. This paper is foundational to your work.

ADD COMMENTlink written 4.9 years ago by anin.gregory70
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