Question: What Is The Difference Between Refseq And Ensembl Database?
3
gravatar for hicsuntdrac0nis
5.5 years ago by
hicsuntdrac0nis210 wrote:

I'm comparing some transcript data between RefSeq and Ensembl. Ensembl seems to have many more isoforms and transcripts than RefSeq. I'm confused on exactly what the difference is because some properties between the untranslated regions and the coding regions are different between the two.

ensembl database refseq • 12k views
ADD COMMENTlink modified 5.5 years ago by Neilfws48k • written 5.5 years ago by hicsuntdrac0nis210
5
gravatar for Neilfws
5.5 years ago by
Neilfws48k
Sydney, Australia
Neilfws48k wrote:

As discussed in Download The List Of All Ensembl Genes And Difference Between Refseq And Ensembl Genes:

Ensembl genes are based partly on RefSeq, partly on UniProt, and partly on Havana manual annotation

so you should not expect the two resources to be equivalent.

Best to read the documentation and use the help features for each database:

If you search the Ensembl Help link for "refseq" you'll find lots of useful information. The basic difference is that RefSeq is a collection of non-redundant, curated mRNA models, whereas Ensembl is a database containing more gene models from multiple sources, mapped to the reference genome.

ADD COMMENTlink written 5.5 years ago by Neilfws48k
1
gravatar for Tky
5.5 years ago by
Tky980
Japan
Tky980 wrote:

Please check Ensembl-Ids Vs. Entrez-Ids, may this helps

ADD COMMENTlink written 5.5 years ago by Tky980

That question has more to do with Entrez Gene than Entrez RefSeq.

ADD REPLYlink written 5.5 years ago by Neilfws48k
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