I used to work in a high-throughput screening facility. My work was mainly on the lab automation side of things, and as I got more into programming I got recruited into the high-throughput sequencing realm. I enjoyed working in high-throughput screening though, and one thing that intrigued me was all of the hype around virtual high-throughput screening. In theory it sounded great: just model atomic interactions and save the copious amounts of cash required to physically screen a compound library. One postdoc with whom I worked took a job with a company in New Mexico which studied this, but he can't disclose anything he's working on, much to my chagrin.
Anyone care to share their perspective?