Question: Transcription Factor And Corresponding Target Gene Resources
gravatar for Woa
4.5 years ago by
United States
Woa2.6k wrote:

Hello I'm looking for transcription factor resource that would give a list of transcription factors and their corresponding target gene(s).

The species I'm mostly interested in are Mouse and Rat.

I've found this database but there can be a better resource.


gene transcription target • 3.7k views
ADD COMMENTlink modified 4.5 years ago by Charles Warden4.9k • written 4.5 years ago by Woa2.6k
gravatar for Charles Warden
4.5 years ago by
Charles Warden4.9k
Duarte, CA
Charles Warden4.9k wrote:

In general, there are databases like TRANSFAC and JASPAR for transcription factor binding motifs, and various tools that utilize the matrices present in those databases.

I think this interface provides the functionaity that you are looking for:

More commonly, I tend to work with lists of differentially expressed genes, and I am looking for what motifs are enriched in a given gene list. GATHER is one good, open-source tool for doing this (although there certainly are others):

If you are interested in de novo prediction of enriched motifs, I would recommend SCOPE:

ADD COMMENTlink written 4.5 years ago by Charles Warden4.9k
Please log in to add an answer.


Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1369 users visited in the last hour