While you could write some Perl to do this, if you are only interested in some basic information about the sequences then using a existing tool such as the EMBOSS program infoseq is probably going to be easier. For example, getting the sequence length and GC composition:
$ infoseq -auto -only -accession -length -pgc em_rel_est_env Accession Length %GC AB446243 43 55.81 AB446244 174 59.20 AB446245 195 52.31 AB446246 205 61.46 AB446247 133 60.15 AB446248 106 62.26 AB446249 73 63.01 AB446250 216 57.41 ...
While this example uses white-space padded columns, the '-nocolumns' and '-delimiter' options can be used to produce a delimited table for easier parsing, and the header line detailing the columns can be disabled using the '-noheading' option.
If you are interested in extracting other information from the sequences, as a staring point try looking at the other EMBOSS programs: http://emboss.open-bio.org/html/use/apbs02.html
From Perl you could use 'system()' to run an EMBOSS program externally, or you could use the EMBOSS support in BioPerl to run EMBOSS programs (see http://www.bioperl.org/wiki/HOWTO:Beginners#Using_EMBOSS_applications_with_Bioperl).
Alternativly you could use the sequence information support available in BioPerl, see http://www.bioperl.org/wiki/HOWTO:Beginners#Obtaining_basic_sequence_statistics.