Question: Mirna-Target Gene Network
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gravatar for Mandar
5.6 years ago by
Mandar160
pune
Mandar160 wrote:

What bioinformatics analysis can be carried out with human miRNA -target gene network?

gene network • 3.4k views
ADD COMMENTlink modified 5.6 years ago by Jonathanjacobs210 • written 5.6 years ago by Mandar160
1

With just a group of putative miRNA targets alone, or do you also have paired expression data?

ADD REPLYlink written 5.6 years ago by Devon Ryan89k

I'm quite sure there are a lot of possibilities for analysis -- what do you want to do with your data? A more specific question would help us give you more input than an open ended question like this.

ADD REPLYlink written 5.6 years ago by Josh Herr5.6k

I just have a list of diabetis candidate genes and miRNAs targeting these genes now i want to see the regulation in the network.how to go about it?

ADD REPLYlink written 5.6 years ago by Mandar160
1
gravatar for Jonathanjacobs
5.6 years ago by
Rockville, MD
Jonathanjacobs210 wrote:

If you have just miRNA profiling data (small RNA-Seq data perhaps?) the types of analysis is fairly limited since the important piece of the puzzle is the actual effect on the transcriptome (typically). If you have paired expression data from the --same samples--, then I would recommend looking into using Ingenuity Pathway Analysis suite (IPA). Alternatively, if you're on a tight budget and are looking for an open source option - there's a link list page here (http://integrated-analysis.gene-quantification.info) than can get you started.

ADD COMMENTlink written 5.6 years ago by Jonathanjacobs210
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