Forum: (Closed) Epigenomics Contest: How Many Flaws Can You Find In This Paper?
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gravatar for ugly.betty77
7.0 years ago by
ugly.betty771.0k
United States
ugly.betty771.0k wrote:

Mapping Human Epigenomes

As the second dimension to the genome, the epigenome contains key information specific to every type of cells. Thousands of human epigenome maps have been produced in recent years thanks to rapid development of high throughput epigenome mapping technologies. In this review, we discuss the current epigenome mapping toolkit and utilities of epigenome maps. We focus particularly on mapping of DNA methylation, chromatin modification state, and chromatin structures, and emphasize the use of epigenome maps to delineate human gene regulatory sequences and developmental programs. We also provide a perspective on the progress of the epigenomics field and challenges ahead.

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ADD COMMENTlink modified 7.0 years ago • written 7.0 years ago by ugly.betty771.0k
6

This kind of axe-grinding post doesn't have any place here. If you'd like to offer critiques of this science and start a discussion, that's fine, but just posting a link and calling it "junk" isn't really constructive.

ADD REPLYlink written 7.0 years ago by Chris Miller21k

Not sure what is 'axe-grinding' here. It is a review paper published in a major journal and NIH is ready to spend nearly a billion dollar on its premise. Therefore, the paper should be relevant for everyone working on bioinformatics and competing for govt money. Moreover, anyone is free to comment that it is a great and flawless paper, and Biostar's voting mechanism will pick such an answer as the best one, if that is appropriate. If instead I wrote bad things about it, that would have been axe-grinding IMHO.

Instead of blocking questions you do not like, why don't you post a reply that it is a flawless paper and explain why you think so?

ADD REPLYlink written 7.0 years ago by ugly.betty771.0k
5

You're posting this article hoping to pick some sort of fight, as you've done previously (Why Does Biostar Cover Questions on Epigenetics, but not Intelligent Design?). That's not cool. There is probably a good post to be made that outlines specific criticisms of the paper and starts a healthy discussion about the merits of the science. This, unfortunately, is not that post.

ADD REPLYlink modified 7.0 years ago • written 7.0 years ago by Chris Miller21k
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