Question: Protein-Protein Interaction Prediction
1
gravatar for elb83
5.7 years ago by
elb8380
elb8380 wrote:

Hi guys, I have a list of protein names and I would like to know if they interact physically. Many bioinformatic tools are available to perform such a prediction. What is the best tool in terms of experimentally validated interactions and update?

Thanks in advance,

Best e.

prediction • 9.6k views
ADD COMMENTlink modified 5.7 years ago by Arnaud Ceol840 • written 5.7 years ago by elb8380
3
gravatar for Arnaud Ceol
5.7 years ago by
Arnaud Ceol840
Milan, Italy
Arnaud Ceol840 wrote:

You should have a look at this article that we wrote recently: the second part is about prediction tools: http://www.sciencedirect.com/science/article/pii/S0959440X13001267

About databases, the STRING (http://string.embl.de/) database integrates several prediction tools. From http://www.ebi.ac.uk/Tools/webservices/psicquic/view/main.xhtml, you have access to many protein interaction databases, some of which are doing predictions. If you look at experimental databases, be careful as they don't contain only physical interactions.

ADD COMMENTlink written 5.7 years ago by Arnaud Ceol840

Thank you a lot!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!

ADD REPLYlink written 5.7 years ago by elb8380
1
gravatar for ancient_learner
5.7 years ago by
India
ancient_learner610 wrote:

what is your model organism? you can check this http://thebiogrid.org/ link

ADD COMMENTlink modified 5.7 years ago • written 5.7 years ago by ancient_learner610
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