Bam Files Of Exomes From 1000 Genomes Project

Question

[Jorjial]

Hi everybody, I'm working with some exome sequencing data. I'd like to compare my results with data from 1000 genomes project. I have not found any public list of alignment files in bam format. But, if you browse the samples data directories in the FTP server, you can find some alignment files in bam format. For example, in this directory ftp://ftp.1000genomes.ebi.ac.uk/vol1...ome_alignment/. Does anyone know if these files are are the definitive ones? Or some of them are partial alignments and they are going to complete them? Thanks a lot! Jrg

Answer 1

[Jorjial]

This is the answer from the 1000 genomes project: "The exome BAMs you found on the ftp site are a part of the Phase I data. It is incomplete. Some samples don't have exome BAMs yet; some samples have BAMs but the BAM may be updated due to additional sequences are added in the future. "

[Laura]

This is correct. The exome analysis pipeline only started running recently but we hope to release an alignment index which will describe the bams that will be used as part of the phase 1 analysis in the next month

[Jorjial]

Laura, thanks for the information.