I´d like to know if someone has some hint to simulate introducing CNVs into genome reference in way as near to actual as possible.
Thanks in advance.
I'm trying SCNVSim. Did you find any other tools?
I recommend PEMer (Gerstein lab).
PEMer has SV-simulation tool which lets you to specify CNV information you want (CNV type, size, how many).
I'm using RSVSim, now. For me, it was the best and easiest to use, so far.