I have a protein whose structure has been resolved and the structure of the complex it forms with a known target is also known. There is suspicion that it is able to bind other proteins. Structure focused analysis is new to me, can anyone make suggestions for some approaches that can be used to hunt for potential targets of this protein?
In other words, can I use the knowledge of the structure for the protein in question and its only known target to predict other binding interactions. This protein, CPXV203, is a viral protein so I would be interested in human targets. This adds a challenge to the analysis since there is only a few structures of CPXV203 known and only one interaction, binding MHC-1.