Question: (Closed) Bioinformatics Project Idea
1
gravatar for Graslevy
8.1 years ago by
Graslevy240
UK
Graslevy240 wrote:

Possible Duplicate:
Suggest final year project

Hey Guys, I hope it is appropriate to ask for suggestions for a good final year project idea. As a bioinformatics student, I am yet to establish the concrete links between my modules. So any ideas/suggestions will be very helpful...Thanks.

project • 9.9k views
ADD COMMENTlink modified 8.0 years ago by Aleksandr Levchuk3.1k • written 8.1 years ago by Graslevy240
3

I think you'll have better luck if you take something you found interesting and pursue that

ADD REPLYlink written 8.1 years ago by Gww2.6k
2

You might want to check out this question: http://biostar.stackexchange.com/questions/6153/suggest-final-year-project I hope yours is voted down a little less heavily.

ADD REPLYlink written 8.1 years ago by Chris Evelo10.0k
2

To add to that, the issue with such a question is that we don't know what your skills are and what interests you. If you give (a lot) more detail, you will get a useful answer. If you leave it like this, it's likely to be closed as a duplicated of the one Chris mentioned.

ADD REPLYlink written 8.1 years ago by Michael Schubert6.9k
2

A lot of bioinformatics is indeed the use of BLAST and other existing software. It's how you use it that counts. Anyway, this is a duplicate and must be closed as such. And yes, vague questions lead to few answers.

ADD REPLYlink written 8.1 years ago by Neilfws48k
2

What about contributing to an open source bioinformatics project?

Or how about creating a site/repository for bioinformatics project ideas, where biologists can suggest/request software/scripts and students can find things to do?

ADD REPLYlink written 8.1 years ago by Yannick Wurm2.3k

Thanks for your comments. I appreciate the difficulty in responding to vague requests like this one. I am sure the course will make sense to me soon but so far my modules have either focused on genomics or programming languages. I am hesistant to conclude that my course is all about using existing software or BLAST. I have java certifications but most comments on biostar make little/no mention of java as a relevant language. Any suggestions pointing me in the right direction will help me understand the links and perhaps come up with a project idea...Thanks again.

ADD REPLYlink written 8.1 years ago by Graslevy240
2
gravatar for Aleksandr Levchuk
8.1 years ago by
United States
Aleksandr Levchuk3.1k wrote:

It does depend on your type of skill and area of interest but I will mention one idea: counting frequencies of various amino-acid features in Uniprot (15 million proteins) is really interesting as a starter project.

In my data-mining project I counted the frequency of 7-mers in Uniprot https://github.com/alevchuk/nmercount-classifier (in a sample of 10% of Uniprot)

Some patterns that show up are really mysterious and intriguing (e.g. these 3 clusters for the 2 and 3-mer contns). And the fluid-like shape changes of the data as the n in n-mer is increased.

Perhaps you could do something similar but break it up into the 3 domains of life for example (the species is known for each protein in Uniprot).

ADD COMMENTlink modified 8.1 years ago by Neilfws48k • written 8.1 years ago by Aleksandr Levchuk3.1k
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