Question: (Closed) Bioinformatics Project Idea
gravatar for Graslevy
8.1 years ago by
Graslevy240 wrote:

Possible Duplicate:
Suggest final year project

Hey Guys, I hope it is appropriate to ask for suggestions for a good final year project idea. As a bioinformatics student, I am yet to establish the concrete links between my modules. So any ideas/suggestions will be very helpful...Thanks.

project • 9.9k views
ADD COMMENTlink modified 8.0 years ago by Aleksandr Levchuk3.1k • written 8.1 years ago by Graslevy240

I think you'll have better luck if you take something you found interesting and pursue that

ADD REPLYlink written 8.1 years ago by Gww2.6k

You might want to check out this question: I hope yours is voted down a little less heavily.

ADD REPLYlink written 8.1 years ago by Chris Evelo10.0k

To add to that, the issue with such a question is that we don't know what your skills are and what interests you. If you give (a lot) more detail, you will get a useful answer. If you leave it like this, it's likely to be closed as a duplicated of the one Chris mentioned.

ADD REPLYlink written 8.1 years ago by Michael Schubert6.9k

A lot of bioinformatics is indeed the use of BLAST and other existing software. It's how you use it that counts. Anyway, this is a duplicate and must be closed as such. And yes, vague questions lead to few answers.

ADD REPLYlink written 8.1 years ago by Neilfws48k

What about contributing to an open source bioinformatics project?

Or how about creating a site/repository for bioinformatics project ideas, where biologists can suggest/request software/scripts and students can find things to do?

ADD REPLYlink written 8.1 years ago by Yannick Wurm2.3k

Thanks for your comments. I appreciate the difficulty in responding to vague requests like this one. I am sure the course will make sense to me soon but so far my modules have either focused on genomics or programming languages. I am hesistant to conclude that my course is all about using existing software or BLAST. I have java certifications but most comments on biostar make little/no mention of java as a relevant language. Any suggestions pointing me in the right direction will help me understand the links and perhaps come up with a project idea...Thanks again.

ADD REPLYlink written 8.1 years ago by Graslevy240
gravatar for Aleksandr Levchuk
8.1 years ago by
United States
Aleksandr Levchuk3.1k wrote:

It does depend on your type of skill and area of interest but I will mention one idea: counting frequencies of various amino-acid features in Uniprot (15 million proteins) is really interesting as a starter project.

In my data-mining project I counted the frequency of 7-mers in Uniprot (in a sample of 10% of Uniprot)

Some patterns that show up are really mysterious and intriguing (e.g. these 3 clusters for the 2 and 3-mer contns). And the fluid-like shape changes of the data as the n in n-mer is increased.

Perhaps you could do something similar but break it up into the 3 domains of life for example (the species is known for each protein in Uniprot).

ADD COMMENTlink modified 8.1 years ago by Neilfws48k • written 8.1 years ago by Aleksandr Levchuk3.1k
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