**240**wrote:

I've used MatrixEQTL to find eQTLs and got the p-values. I ran these p-values through GenABEL to get inflation factor lambda. However, what to do next? Based on GWAS analysis, I should divide each Chi-square statistics with this factor, regenerate p-values, and calculate q-values, is it correct? However, for eQTLs, I only have t-stat, should I use t-stat to do the same thing (new_pval = pt ( -abs ( t-stat / lambda ), df ) * 2 ) ? Thanks a lot.

**2.3k**• written 5.5 years ago by Zhenyu Zhang •

**240**