HI,
GO is a database with a hierarchy structure. the upper level terms include the lower ones. I want to trim this tree at certain level to remove the redundancy. any tools to do this trimming process?
HI,
GO is a database with a hierarchy structure. the upper level terms include the lower ones. I want to trim this tree at certain level to remove the redundancy. any tools to do this trimming process?
Hi hanguangchun,
If you want to remove redundancy between enriched terms in your output you could try the tool GO Trimming outlined in "GO Trimming: Systematically reducing redundancy in large Gene Ontology datasets" http://www.biomedcentral.com/1756-0500/4/267
with software provided here (also linked in the article): http://lucy.ceh.uvic.ca/go_trimming/cbr_go_trimming.py