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Question: Go Tree Trimming
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gravatar for ewre
7.0 years ago by
ewre • 240
United States
ewre • 240 wrote:

HI,

GO is a database with a hierarchy structure. the upper level terms include the lower ones. I want to trim this tree at certain level to remove the redundancy. any tools to do this trimming process?
trimming gene-ontology • 2.7k views
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modified 6.6 years ago by Ben Sutherland • 10 • written 7.0 years ago by ewre • 240
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gravatar for Ben Sutherland
6.6 years ago by
Ben Sutherland • 10
Canada
Ben Sutherland • 10 wrote:

Hi hanguangchun,

If you want to remove redundancy between enriched terms in your output you could try the tool GO Trimming outlined in "GO Trimming: Systematically reducing redundancy in large Gene Ontology datasets" http://www.biomedcentral.com/1756-0500/4/267

with software provided here (also linked in the article): http://lucy.ceh.uvic.ca/go_trimming/cbr_go_trimming.py
ADD COMMENT • link written 6.6 years ago by Ben Sutherland • 10

Hi,

I would like to remove redundancy between enriched terms, but GO Trimming it's no longer working, the analysis starts and never ends. It might be because the database is too old ? Do you have a more recent database for Go Trimming ?

Thanks a lot, Regards, WS

ADD REPLY • link modified 16 months ago • written 16 months ago by wilfried.souleyreau • 0
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