The effect of metabolomics on other omics

Question

[mrashad]

Dears,

I am studying the relation between metabolomics and other omics, while I am reading this paper:

https://cancerandmetabolism.biomedcentral.com/articles/10.1186/s40170-016-0143-y

I couldn't understand the transcriptional regulation and epigenomic interactions in figure 2 Could anyone help me, please?

[mrashad]

I understood it, as the transcription factors (proteins) help in the transcription of DNA to RNA and in epigenomics interactions: there are proteins like Histone acetyltransferases (HATs) and Histone deacetylases (HDACs)

https://epigenie.com/key-epigenetic-players/chromatin-modifying-and-dna-binding-proteins/