Genes whose names starts with AL

Question

[sofia.gonzalezm]

Hi!!

I was analyzing a megabase for a project, when a I realise that there were some genes whose names starts with "AL", such as AL121750.1 or AL390065.2. Although I've been searching for a relation between these genes, it seems that they are not related.

However, it doesn't seem to be a casualty. I was wondering if the name refers to an experiment in some institution... but I still can't find anything.

I'm desperate to find an explanation, so I've thought about asking for your help.

Thank you in advance. Sofía.

The link of the megabase is: https://www.ensembl.org/Homo_sapiens/Location/View?db=core;g=ENSG00000197386;r=4:3041363-3243960

Answer 1

[GenoMax]

Looks like AL accession numbers were originally assigned by EMBL for

AL,BX,CR,CT,CU,FP,FQ,FR          EMBL        Genome project data

Locations of these are near each other on Chromosome 4. Currently mapping to following entries.

Using EntrezDirect:

$ esearch -db gene -query "AL390065" | efetch | grep -e "Official" -e "Annotation"
Official Symbol: HTT and Name: huntingtin [Homo sapiens (human)]
Annotation: Chromosome 4 NC_000004.12 (3074681..3243960)
Official Symbol: ADD1 and Name: adducin 1 [Homo sapiens (human)]
Annotation: Chromosome 4 NC_000004.12 (2843844..2930065)
Official Symbol: GRK4 and Name: G protein-coupled receptor kinase 4 [Homo sapiens (human)]
Annotation: Chromosome 4 NC_000004.12 (2963504..3040760)
Official Symbol: NOP14 and Name: NOP14 nucleolar protein [Homo sapiens (human)]
Annotation: Chromosome 4 NC_000004.12 (2937936..2963506, complement)
Official Symbol: MFSD10 and Name: major facilitator superfamily domain containing 10 [Homo sapiens (human)]
Annotation: Chromosome 4 NC_000004.12 (2930556..2934854, complement)
Official Symbol: HTT-AS and Name: HTT antisense RNA [Homo sapiens (human)]
Annotation: Chromosome 4 NC_000004.12 (3063246..3074514, complement)
Official Symbol: NOP14-AS1 and Name: NOP14 antisense RNA 1 [Homo sapiens (human)]
Annotation: Chromosome 4 NC_000004.12 (2935546..2951078)
Official Symbol: RNU6-204P and Name: RNA, U6 small nuclear 204, pseudogene [Homo sapiens (human)]
Annotation: Chromosome 4 NC_000004.12 (3044101..3044207)

[Emily]

These are soon going to be retired in Ensembl