Create Mutational signature plot from vcf file.

Question

[nhaus]

Hello,

I have a vcf file with thousands of mutations (mouse) and I would like to represent these mutations in a plot very similar to this:

I tried to search for packages that provide such a function, but so far I did not find any. I only found packages which try to infer the mutational signatures in my data, but I really just want the visual representation, as in the plot above.

If anyone could point me to a package that has such a function, I would be very happy.

Cheers!

Answer 1

[jared.andrews07]

The mutSignatures R package has that visual.

Answer 2

[amitpande74]

tried this ?

comutplotter

[nhaus]

Unfortunately, it does not seem like this tool outputs this particular plot.

Answer 3

[nhaus]

If someone comes across this later: I ended up using MutationalPatterns which provides the function plot_96_profile, which does what I want.