IGH on Ensembl

Question

[chaochao]

For NCBI, searching on "IGH" with Entrez returns results including NG_001019, which is about 1.29 Mbp of chr 14. Nonetheless, searching with ensembl rest api for IGH (http://rest.ensembl.org/lookup/symbol/homo_sapiens/IGH) there is no record. What should be the gene symbol to search for IGH sequence on Ensembl? Thank you!

Answer 1

[Emily]

Immunoglobulins are annotated differently in NCBI compared to Ensembl. While NCBI annotate one large IGH locus containing all the different IGH pieces, Ensembl annotate each fragment as one gene