I have the following type of file
ID var Beta_1 Beta_2 Beta_3 .... Beta_100 rs1 A -0.6 0.0 0.3 ... 0.2 rs2 G 0.4 0.2 0.0 ... -0.7 ...
I would like to use the --score function of plink to compute PRS for each column.
My main problem is that I can run plink column by column with something like
plink --vcf chr1.vcf.gz --score score.txt 1 2 3
But that requires loading each chromosome per column Beta_k which takes a lot of time. Is there a simple way to parse the different columns and to compute the prs for each column?