I'm wondering if there's a way to calculate the optimal number of samples per condition for a RIP-seq experiment. I haven't come across any R-package or method that would do power calculations although there exists one for ChIP-seq but it's not a very straightforward approach:
Zuo C, Keleş S. A statistical framework for power calculations in ChIP-seq experiments. Bioinformatics. 2014
Does anyone know if there is a recommendation on sample size for RIP-seq?