I know that when species are not very close to each other, hmmer will be a great tool to search for ortholog. However, I have more than 100 different types of gene of interest. I just want a really quick search to find "potential" orthologs from two organisms which belong to the same phylum. I wonder will blastp work if I apply stringent evalue cutoff 1e-10 and piden of 50? Any criticism, suggestion on other easy tools and opinion are welcome.