What is the most convenient way to interact with ncbi?

Question

[Vladimir Leshuk]

What is the most convenient way to interact with ncbi through python, R, or cmd? Do you use special packages/programs when you need to download something or get some information?

I've lost myself in the heap of available programs. for example, I found that 'dataset' (program from ncbi, but It seems that it has some problems) and biopython can partly satisfy me. Do you use these programs or something similar?

Answer 1

[GenoMax]

NCBI also makes available EntrezDirect. That is probably the most seamless way to interact programmatically with NCBI. What kind of problems did you have with datasets. That is mainly meant to be used for genome level information. It would also help to describe what kind of "interaction" are you planning to do with NCBI.