I have large paired-end fastq files (13 GB each) obtained from Illumina sequencing of a bacterial genome.
I am running Unicycler to assemble these WGS data. However, when it uses spades-hammer, I got the following error message:
The reads contain too many k-mers to fit into available memory. You need approx. 13.0774GB of free RAM to assemble your dataset
By any chance, is there a way to solve this issue?
Thank you so much for your help!