High values of Chao1 index

Question

[marc.acfz]

It´s possible to have a values of Chao1 index between 41,000 - 51,000 in a 16s ARNr NGS V4 region sample?

I´m estimating microbiome abundance with mothour sofware but I haven´t seen those Chao1 values in other related papers.

I would appreciate some help

Thanks!