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22 months ago
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I keep running into uses of "multiplex" in genetics and genomics papers, and while I get the basic idea of the word in general (I think), I don't really understand what it means in genomics/genetics.
For example, from this paper:
"In addition, many existing digital molecule counting methods such as digital PCR, digital microarray profiling and direct single-molecule sequencing cannot be effectively multiplexed and are thus generally only applicable to measuring one or few molecular species from many samples, or many species from a single sample."
An example can be given to you with Multiplex Sequencing like
So is an assumption here that before mixing, each original species' sample will have an identifying barcode attache?
Yes, barcoding samples then mixing and after sequencing, extracting each individual sample.