somatic variant calling with Mutect2
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18 months ago
Elisa • 0

Hi everybody,

I am performing somatic variant calling on NGS data (NGS targeted sequencing performed with Illumina MiSeq) using Mutect2. I do not have the normal match, so I am performing Mutect2 only on tumor samples. The result is a very high number of variant calls which makes me think there's something wrong. So how can I solve this problem? Are there any filtering steps I must perform (I have already performed FilterMutectCalls) ?

Thanks in advance.

calling somatic Mutect2 variant • 358 views
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