assessing relative contribution of samples/ organs towards a diseases in multi-tissue RNAseq
0
0
Entering edit mode
3.3 years ago
cwwong13 ▴ 40

I did an RNAseq on multiple tissues (liver, muscle, heart, kidney, etc) on two groups of mice (disease v.s. control). I wonder are there is a type of analysis I can do so that I can conclude the transcriptomic profile is highly shifted in 1 specific organ? I am not sure whether just a comparison of the crude number of DEGs is a valid way to do it.

e.g. I would like to draw a conclusion: Upon the establishment of the disease, the transcriptomic profile in muscle is the most perturbed, thus we are going to focus on understanding the role of muscle on the disease.

RNAseq • 467 views
ADD COMMENT

Login before adding your answer.

Traffic: 1618 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6