Has anyone ever tested the dragen-gatk version for the human germline genome? If so, have you obtained satisfactory results compared to classic gatk? What steps did you take?
Yes, yes, all recommended!
More precisely ? For the moment there is no official pipeline and i don't found any clue toi begin in term of option and tools to run.
I run :
Haplotypecaller (dragen mode)
But then ?
Hard filter instead of vqsr ? With wich parameter ?
I would like to have some first ideas so as not to start from nothing
We run one sample on both DRAGEN and standard clinical pipeline and compared precision/recall/etc with different parameters.
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