Is it possible to recombine several old scRNA seq studies and answer a biological question i.e. build up a new analysis on the basis of combine analysis of old.
EXAMPLE -I found many single cell RNA seq studies which focus on different tissues.
Can I combine them all to check gene expression of geneX in the different tissues showing relative expression in them.Is it a possible insilico study?
Will there not be a lot of batch effect?If so how can it be avoided?
Will I have to start from gene count or download SRR so that all different scrnaseq studies are quality controlled in the same manner?