Differential expression analysis between two different cohorts
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29 days ago
leticia ▴ 20

Hello , please i have two different datasets: TCGA and another one , i need to do a differential expression of genes between them , is it possible ?

RNA-Seq TCGA R • 357 views
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Maybe, some details about what the data are would be helpful. So what are the conditions you look at, and are these similar between both cohorts.

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Conditions are the same and the cohort is ours , so i want to see the difference in genes between them

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I would use Gene Set Enrichment Analysis. A direct quantitative comparison of the counts is not possible due to batch effects.

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Thanks a lot for your help

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