Also, if the software is open source, would you be willing to pay an individual developer a one-time cost for binaries and email support? Thanks for your time.
Examples of interfaces (Python and Qt) I've developed in the past (while working in academia).
There's definitely a market for GUIs. Note, that you'd enter a field where you compete with organizations with notable sized development teams, for example Galaxy and some dedicated bioinformatics companies.
Thank you. I'm thinking smaller scale and not looking to compete with larger teams or companies, i.e., focusing on a single program to begin with.