Interpretation of Shannon e Index

Question

[Bio_Crap]

Hello, I am trying to calculate the Shannon diversity of resistomes acquired from different matrixes. However, it turns out that there is no difference among them even if the index of each varies a lot. Is this result common? Or should I not trust it and try to calculate via another package?

[Chris Dean]

It is difficult to answer this question without additional information about your study design and methods. Can you share information about this: e.g., sample size, statistical test used, package used to measure your outcome variable, and a full panel figure.