Summary of KEGG functional categories from an annotated genome? Is there a tool for this?
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11 months ago
jmgreenb420 ▴ 10

I have several annotated bacterial genomes that I have been analyzing. I have run them through the web-browser utility BlastKOALA to get KEGG functional annotations. This generates a list of KO numbers and allows exploration of various pathways and maps, however, I am trying to find a way to summarize the functional potential of the overall genome.

Specifically, the results from the tool show a summary page that includes a piechart showing the distrubition of functional categories from the annotation, which is basically what I want. However the data summarized at this point is not provided or accessible in this form to the user. If I explore what is available to me, it is all at a much greater resolution. For example, I want to know how many genes are associated/categorized as "amino acid metabolism" however the resolution of the data I am provided would be "K01079 serB, PSPH; phosphoserine phosphatase [EC:3.1.3.3]" and would require me to manually curate it all to a lower resolution before I can summarize.

Can anyone provide me some insight into other approaches/tools?

genomics KEGG • 423 views
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do you have a list of genes of interest?

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5 months ago
Mallory • 0

Did you ever find a tool/solution for this? I have the exact same question.

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Same here!

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