Download FASTA sequences for known viral reference genomes
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2.5 years ago
adam • 0

I am trying to align unmapped reads in a whole human genome sequence to viral genomes. I stumbled across NCBI's repository of reference genomes at the link below:

https://www.ncbi.nlm.nih.gov/genome/browse/#!/overview/

Is there a way I can download the FASTA sequences for each of these reference genomes? I would only need DNA based viruses, and ones that infect humans

reference-genome virus • 1.3k views
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Thank you for the feedback, I just went back and validated all helpful answers from my previous questions

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2.5 years ago
GenoMax 141k

Take a look at this report file for viral genomes.

I would only need DNA based viruses, and ones that infect humans

You can filter/parse out entries you need from it. Then download the genome sequence using EntrezDirect:

$ efetch -db nuccore -id NC_030449.1 -format fasta
>NC_030449.1 Unidentified circular ssDNA virus, complete genome
AAGTTCTGAGCGTAGGGCTAGTAGATAACGCACGTAGCTCAGATGACCGACGAAGACGGTCCTCGAGTAA
GAAACATAGTATTCATCATCAACGCAATCGATGGGGACGACCTTGTGTCCCAATTGCGTTTGCTCGATTT
CCAACACCCCACGTGGAAGCACGTAAAGTACTGTATCTATCAGCGAGAGTGCGGGGGTGAGGAGAATCGA
ATCCACTTCCAGGGCTACATGGAGTTCCACATCCAGCAGACCTATAAGCAGATTCATGCCATGGAAGGGA
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Thank you!

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