I have short reads from Illumina (paired-end, 150x2). I concatenated the two files (2.3GB each) (since the merging results were not good) before aligning with DIAMOND using blastx on HPC with 88 threads and 270GB RAM. I also added -b 8 -c 1 on the command. It's been running for almost 24 hours now. I'm wondering how long does it take to finish the alignment process? I'm thinking maybe my files are too big? What could be an alternative workaround?