Tumor cell percentage detection tool

Question

[MS]

Hi,

I have done Gatk mutect2 pipeline and get annovar results for ffpe and cfdna samples. I want to determine tumor percentage in my data.

I used maftools inferheterogeneity function but it doesnt give tumor percentage.

I confused a bit can I use maftools results for tumor percentage estimation ör can anyone suggest a tool for this purpose?

Answer 1

[Getting there]

A few tools will do this, control-FREEC, THetA, CloneCNA, ASCAT

Answer 2

[iraun]

I use FACETS for calculating tumor purity :).