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2.4 years ago
star715
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What are R tools/packages I can use to smooth a bigwig plot? I basically want to get bam coverage as bigwig files for every 100bp regions. I am using rtracklayer and genomicAlignment packages to convert bam to bigwig files.
Check the genomation package from Bioconductor which has a
ScoreMatrixBin()to load coverages from bigwig files and bin it over specific intervals.